This course covers the fundamentals of medical imaging from both the processing of digital images and the physics of image formation. Image processing topics covered include: fundamentals of resolution and quantization; linear systems as applied to multi-dimensional continuous and discrete systems including the relationship between the point spread functions and modulation transfer function; point operations such as contrast enhancement, histogram equalization, and H and D curves, geometric operations for distortion correction, including interpolation methods; linear filtering in both the spatial and spatial-frequency domains; and image restoration and inverse filtering. The physics of the following imaging modalities with emphasis on the parameters which effect image quality will be covered: x-ray radiology, MRI, ultrasound, and nuclear medicine.